Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | the enzyme activity is increased in schizophrenia | Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | the enzyme inhibition might have an therapeutic effect in schizophrenia treatment | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-serine + H2O + O2 | Homo sapiens | metabolizaation of the N-methyl D-aspartate receptor co-agonist | 2-oxo-3-hydroxypropionate + NH3 + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
flavoprotein | - |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-serine + H2O + O2 | - |
Homo sapiens | 2-oxo-3-hydroxypropionate + NH3 + H2O2 | - |
? | |
D-serine + H2O + O2 | metabolizaation of the N-methyl D-aspartate receptor co-agonist | Homo sapiens | 2-oxo-3-hydroxypropionate + NH3 + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DAO | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | flavoenzyme | Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | enzyme expression is increased in schizophrenia | up |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme modulates the function of the N-methyl D-aspartate receptor contributing to the involvement of the receptor signalling in schizophrenia | Homo sapiens |