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Literature summary for 1.4.3.3 extracted from

  • Madeira, C.; Freitas, M.E.; Vargas-Lopes, C.; Wolosker, H.; Panizzutti, R.
    Increased brain D-amino acid oxidase (DAAO) activity in schizophrenia (2008), Schizophr. Res., 101, 76-83.
    View publication on PubMed
Search for more literature for 1.4.3.3

Activating Compound

Activating Compound Comment Organism Structure
additional information mean DAAOactivity is 2fold higher in the schizophrenia patients group compared with the control group Homo sapiens

Application

Application Comment Organism
medicine D-serine availability in the nervous system may be altered in schizophrenia because of increased D-amino acid degradation by DAAO Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain cortex
-
 Homo sapiens
-
cerebellum
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alanine + H2O + O2
-
 Homo sapiens pyruvate + NH3 + H2O2
-
 ?
D-serine + H2O + O2
-
 Homo sapiens 2-oxo-3-hydroxypropionic acid + NH3 + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
D-amino acid oxidase
-
 Homo sapiens
DAAO
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Homo sapiens