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Literature summary for 1.4.3.3 extracted from
- D-Amino acid oxidase: structure, catalytic mechanism, and practical application (2005), Biochemistry, 70, 40-54.
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 39300 | - |
x * 39300 | Trigonopsis variabilis |
| 39600 | - |
x * 39600 | Sus scrofa |
| 40000 | - |
x * 40000 | Rhodotorula toruloides |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Acrostalagmus luteoalbus | - |
- |
- |
| Candida parapsilosis | - |
- |
- |
| Fusarium oxysporum | - |
- |
- |
| Rhodotorula toruloides | - |
- |
- |
| Sus scrofa | - |
- |
- |
| Trigonopsis variabilis | - |
- |
- |
| [Candida] boidinii | Q9HGY3 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cephalosporin C + H2O + O2 | 1% of the activity with D-Ala | Fusarium oxysporum | 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 | - |
? |  |
| cephalosporin C + H2O + O2 | 1% of the activity with D-Met | Acrostalagmus luteoalbus | 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 | - |
? | |
| cephalosporin C + H2O + O2 | 13% of the activity with D-Val | Trigonopsis variabilis | 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 | - |
? | |
| cephalosporin C + H2O + O2 | 2% of the activity with D-Met | Rhodotorula toruloides | 7-(5-oxoadipoamido)cephalosporanic acid + NH3 + H2O2 | - |
? | |
| D-Ala + H2O + O2 | best substrate | Candida parapsilosis | pyruvate + NH3 + H2O2 | - |
? | |
| D-Ala + H2O + O2 | best substrate | Fusarium oxysporum | pyruvate + NH3 + H2O2 | - |
? | |
| D-Ala + H2O + O2 | best substrate | [Candida] boidinii | pyruvate + NH3 + H2O2 | - |
? | |
| D-Ala + H2O + O2 | 40% of the activity with D-Pro | Sus scrofa | pyruvate + NH3 + H2O2 | - |
? | |
| D-Ala + H2O + O2 | 57% of the activity with D-Met | Acrostalagmus luteoalbus | pyruvate + NH3 + H2O2 | - |
? | |
| D-Ala + H2O + O2 | 71% of the activity with D-Met | Rhodotorula toruloides | pyruvate + NH3 + H2O2 | - |
? | |
| D-Ala + H2O + O2 | 97% of the activity with D-Val | Trigonopsis variabilis | pyruvate + NH3 + H2O2 | - |
? | |
| D-Arg + H2O + O2 | 2% of the activity with D-Met | Rhodotorula toruloides | 5-guanidino-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Arg + H2O + O2 | 25% of the activity with D-Ala | Candida parapsilosis | 5-guanidino-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Arg + H2O + O2 | 4% of the activity with D-Pro | Sus scrofa | 5-guanidino-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Arg + H2O + O2 | 43% of the activity with D-Val | Trigonopsis variabilis | 5-guanidino-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Arg + H2O + O2 | 7% of the activity with D-Ala | Fusarium oxysporum | 5-guanidino-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Asn + H2O + O2 | 0.18% of the activity with D-Ala | [Candida] boidinii | 2-oxosuccinamate + NH3 + H2O2 | - |
? | |
| D-Asn + H2O + O2 | 2% of the activity with D-Ala | Candida parapsilosis | 2-oxosuccinamate + NH3 + H2O2 | - |
? | |
| D-Asn + H2O + O2 | 3% of the activity with D-Ala | Fusarium oxysporum | 2-oxosuccinamate + NH3 + H2O2 | - |
? | |
| D-Asn + H2O + O2 | 40% of the activity with D-Met | Rhodotorula toruloides | 2-oxosuccinamate + NH3 + H2O2 | - |
? | |
| D-Asn + H2O + O2 | 65% of the activity with D-Val | Trigonopsis variabilis | 2-oxosuccinamate + NH3 + H2O2 | - |
? | |
| D-Asp + H2O + O2 | 7% of the activity with D-Met | Acrostalagmus luteoalbus | oxaloacetate + NH3 + H2O2 | - |
? | |
| D-Cys + H2O + O2 | 1% of the activity with D-Met | Rhodotorula toruloides | 2-oxo-3-sulfanylpropionate + NH3 + H2O2 | - |
? | |
| D-Gln + H2O + O2 | 1% of the activity with D-Pro | Sus scrofa | 2-oxoglutaramate + NH3 + H2O2 | - |
? | |
| D-Gln + H2O + O2 | 15% of the activity with D-Ala | Fusarium oxysporum | 2-oxoglutaramate + NH3 + H2O2 | - |
? | |
| D-Gln + H2O + O2 | 5% of the activity with D-Ala | Candida parapsilosis | 2-oxoglutaramate + NH3 + H2O2 | - |
? | |
| D-Gln + H2O + O2 | 51% of the activity with D-Met | Acrostalagmus luteoalbus | 2-oxoglutaramate + NH3 + H2O2 | - |
? | |
| D-Gln + H2O + O2 | 53% of the activity with D-Met | Rhodotorula toruloides | 2-oxoglutaramate + NH3 + H2O2 | - |
? | |
| D-Gln + H2O + O2 | 81% of the activity with D-Val | Trigonopsis variabilis | 2-oxoglutaramate + NH3 + H2O2 | - |
? | |
| D-Glu + H2O + O2 | 10% of the activity with D-Met | Acrostalagmus luteoalbus | alpha-ketoglutarate + NH3 + H2O2 | - |
? | |
| D-Glu + H2O + O2 | 4% of the activity with D-Met | Rhodotorula toruloides | alpha-ketoglutarate + NH3 + H2O2 | - |
? | |
| D-Glu + H2O + O2 | 4% of the activity with D-Pro | Sus scrofa | alpha-ketoglutarate + NH3 + H2O2 | - |
? | |
| D-Glu + H2O + O2 | 54% of the activity with D-Ala | Candida parapsilosis | alpha-ketoglutarate + NH3 + H2O2 | - |
? | |
| D-Glu + H2O + O2 | 9% of the activity with D-Val | Trigonopsis variabilis | alpha-ketoglutarate + NH3 + H2O2 | - |
? | |
| D-His + H2O + O2 | 14% of the activity with D-Ala | Fusarium oxysporum | 3-(1H-imidazol-4-yl)-2-oxopropanoic acid + NH3 + H2O2 | - |
? | |
| D-His + H2O + O2 | 3% of the activity with D-Pro | Sus scrofa | 3-(1H-imidazol-4-yl)-2-oxopropanoic acid + NH3 + H2O2 | - |
? | |
| D-His + H2O + O2 | 4% of the activity with D-Ala | Candida parapsilosis | 3-(1H-imidazol-4-yl)-2-oxopropanoic acid + NH3 + H2O2 | - |
? | |
| D-His + H2O + O2 | 58% of the activity with D-Met | Rhodotorula toruloides | 3-(1H-imidazol-4-yl)-2-oxopropanoic acid + NH3 + H2O2 | - |
? | |
| D-His + H2O + O2 | 88% of the activity with D-Val | Trigonopsis variabilis | 3-(1H-imidazol-4-yl)-2-oxopropanoic acid + NH3 + H2O2 | - |
? | |
| D-Ile + H2O + O2 | 15% of the activity with D-Met | Acrostalagmus luteoalbus | 3-methyl-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Ile + H2O + O2 | 19% of the activity with D-Ala | Fusarium oxysporum | 3-methyl-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Ile + H2O + O2 | 35% of the activity with D-Pro | Sus scrofa | 3-methyl-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Ile + H2O + O2 | 56% of the activity with D-Met | Rhodotorula toruloides | 3-methyl-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Ile + H2O + O2 | 76% of the activity with D-Val | Trigonopsis variabilis | 3-methyl-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Leu + H2O + O2 | 21% of the activity with D-Pro | Sus scrofa | 4-methyl-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Leu + H2O + O2 | 29% of the activity with D-Ala | Fusarium oxysporum | 4-methyl-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Leu + H2O + O2 | 32% of the activity with D-Val | Trigonopsis variabilis | 4-methyl-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Leu + H2O + O2 | 42% of the activity with D-Met | Acrostalagmus luteoalbus | 4-methyl-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Leu + H2O + O2 | 57% of the activity with D-Met | Rhodotorula toruloides | 4-methyl-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Leu + H2O + O2 | 7% of the activity with D-Ala | [Candida] boidinii | 4-methyl-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Leu + H2O + O2 | 92% of the activity with D-Ala | Candida parapsilosis | 4-methyl-2-oxopentanoate + NH3 + H2O2 | - |
? | |
| D-Lys + H2O + O2 | 17% of the activity with D-Val | Trigonopsis variabilis | ? | - |
? | |
| D-Lys + H2O + O2 | 2% of the activity with D-Pro | Sus scrofa | ? | - |
? | |
| D-Lys + H2O + O2 | 25% of the activity with D-Ala | Candida parapsilosis | ? | - |
? | |
| D-Lys + H2O + O2 | 5% of the activity with D-Met | Rhodotorula toruloides | ? | - |
? | |
| D-Met + H2O + O2 | best substrate | Rhodotorula toruloides | 4-methylthio-2-oxobutanoate + NH3 + H2O2 | - |
? | |
| D-Met + H2O + O2 | best substrate | Acrostalagmus luteoalbus | 4-methylthio-2-oxobutanoate + NH3 + H2O2 | - |
? | |
| D-Met + H2O + O2 | 14% of the activity with D-Ala | [Candida] boidinii | 4-methylthio-2-oxobutanoate + NH3 + H2O2 | - |
? | |
| D-Met + H2O + O2 | 28% of the activity with D-Ala | Fusarium oxysporum | 4-methylthio-2-oxobutanoate + NH3 + H2O2 | - |
? | |
| D-Met + H2O + O2 | 75% of the activity with D-Pro | Sus scrofa | 4-methylthio-2-oxobutanoate + NH3 + H2O2 | - |
? | |
| D-Met + H2O + O2 | 78% of the ativity with D-Val | Trigonopsis variabilis | 4-methylthio-2-oxobutanoate + NH3 + H2O2 | - |
? | |
| D-Phe + H2O + O2 | 1.5% of the activity with D-Ala | [Candida] boidinii | phenylpyruvate + NH3 + H2O2 | - |
? | |
| D-Phe + H2O + O2 | 19% of the activity with D-Ala | Candida parapsilosis | phenylpyruvate + NH3 + H2O2 | - |
? | |
| D-Phe + H2O + O2 | 36% of the activity with D-Val | Trigonopsis variabilis | phenylpyruvate + NH3 + H2O2 | - |
? | |
| D-Phe + H2O + O2 | 41% of the activity with D-Ala | Fusarium oxysporum | phenylpyruvate + NH3 + H2O2 | - |
? | |
| D-Phe + H2O + O2 | 50% of the activity with D-Met | Acrostalagmus luteoalbus | phenylpyruvate + NH3 + H2O2 | - |
? | |
| D-Phe + H2O + O2 | 79% of the activity with D-Met | Rhodotorula toruloides | phenylpyruvate + NH3 + H2O2 | - |
? | |
| D-Phe + H2O + O2 | 84% of the activity with D-Pro | Sus scrofa | phenylpyruvate + NH3 + H2O2 | - |
? | |
| D-proline + H2O + O2 | best substrate | Sus scrofa | 2-oxopentanoic acid + NH3 + H2O2 | - |
? | |
| D-proline + H2O + O2 | 1.4% of the activity with D-Ala | [Candida] boidinii | 2-oxopentanoic acid + NH3 + H2O2 | - |
? | |
| D-proline + H2O + O2 | 22% of the activity with D-Ala | Fusarium oxysporum | 2-oxopentanoic acid + NH3 + H2O2 | - |
? | |
| D-proline + H2O + O2 | 25% of the activity with D-Val | Trigonopsis variabilis | 2-oxopentanoic acid + NH3 + H2O2 | - |
? | |
| D-proline + H2O + O2 | 4% of the activity with D-Met | Acrostalagmus luteoalbus | 2-oxopentanoic acid + NH3 + H2O2 | - |
? | |
| D-proline + H2O + O2 | 41% of the activity with D-Ala | Candida parapsilosis | 2-oxopentanoic acid + NH3 + H2O2 | - |
? | |
| D-proline + H2O + O2 | 57% of the activity with D-Met | Rhodotorula toruloides | 2-oxopentanoic acid + NH3 + H2O2 | - |
? | |
| D-Ser + H2O + O2 | 18% of the activity with D-Ala | Fusarium oxysporum | 2-oxo-3-hydroxypropionate + NH3 + H2O2 | - |
? | |
| D-Ser + H2O + O2 | 18% of the activity with D-Pro | Sus scrofa | 2-oxo-3-hydroxypropionate + NH3 + H2O2 | - |
? | |
| D-Ser + H2O + O2 | 22% of the activity with D-Val | Trigonopsis variabilis | 2-oxo-3-hydroxypropionate + NH3 + H2O2 | - |
? | |
| D-Ser + H2O + O2 | 32% of the activity with D-Ala | [Candida] boidinii | 2-oxo-3-hydroxypropionate + NH3 + H2O2 | - |
? | |
| D-Ser + H2O + O2 | 41% of the activity with D-Met | Rhodotorula toruloides | 2-oxo-3-hydroxypropionate + NH3 + H2O2 | - |
? | |
| D-Ser + H2O + O2 | 6% of the activity with D-Ala | Candida parapsilosis | 2-oxo-3-hydroxypropionate + NH3 + H2O2 | - |
? | |
| D-Ser + H2O + O2 | 9% of the activity with D-Met | Acrostalagmus luteoalbus | 2-oxo-3-hydroxypropionate + NH3 + H2O2 | - |
? | |
| D-threonine + H2O + O2 | 1.2% of the activity with D-Ala | [Candida] boidinii | 2-oxo-3-hydroxybutyrate + NH3 + H2O2 | - |
? | |
| D-threonine + H2O + O2 | 10% of the activity with D-Met | Rhodotorula toruloides | 2-oxo-3-hydroxybutyrate + NH3 + H2O2 | - |
? | |
| D-threonine + H2O + O2 | 2% of the activity with D-Ala | Fusarium oxysporum | 2-oxo-3-hydroxybutyrate + NH3 + H2O2 | - |
? | |
| D-threonine + H2O + O2 | 2% of the activity with D-Pro | Sus scrofa | 2-oxo-3-hydroxybutyrate + NH3 + H2O2 | - |
? | |
| D-threonine + H2O + O2 | 4% of the activity with D-Val | Trigonopsis variabilis | 2-oxo-3-hydroxybutyrate + NH3 + H2O2 | - |
? | |
| D-Trp + H2O + O2 | 14% of the activity with D-Ala | Fusarium oxysporum | indol-3-pyruvate + NH3 + H2O2 | - |
? | |
| D-Trp + H2O + O2 | 2% of the activity with D-Pro | Sus scrofa | indol-3-pyruvate + NH3 + H2O2 | - |
? | |
| D-Trp + H2O + O2 | 38% of the activity with D-val | Trigonopsis variabilis | indol-3-pyruvate + NH3 + H2O2 | - |
? | |
| D-Trp + H2O + O2 | 56% of the activity with D-Met | Rhodotorula toruloides | indol-3-pyruvate + NH3 + H2O2 | - |
? | |
| D-Trp + H2O + O2 | 9% of the activity with D-Ala | Candida parapsilosis | indol-3-pyruvate + NH3 + H2O2 | - |
? | |
| D-Tyr + H2O + O2 | 17% of the activity with D-Val | Trigonopsis variabilis | 4-hydroxyphenylpyruvic acid + NH3 + H2O2 | - |
? | |
| D-Tyr + H2O + O2 | 26% of the activity with D-Met | Rhodotorula toruloides | 4-hydroxyphenylpyruvic acid + NH3 + H2O2 | - |
? | |
| D-Tyr + H2O + O2 | 4% of the activity with D-Pro | Sus scrofa | 4-hydroxyphenylpyruvic acid + NH3 + H2O2 | - |
? | |
| D-Tyr + H2O + O2 | 6% of the activity with D-Ala | Candida parapsilosis | 4-hydroxyphenylpyruvic acid + NH3 + H2O2 | - |
? | |
| D-Tyr + H2O + O2 | 8% of the activity with D-Ala | Fusarium oxysporum | 4-hydroxyphenylpyruvic acid + NH3 + H2O2 | - |
? | |
| D-Val + H2O + O2 | best substrate | Trigonopsis variabilis | alpha-ketoisovalerate + NH3 + H2O2 | - |
? | |
| D-Val + H2O + O2 | 15% of the activity with D-Ala | Candida parapsilosis | alpha-ketoisovalerate + NH3 + H2O2 | - |
? | |
| D-Val + H2O + O2 | 28% of the activity with D-Pro | Sus scrofa | alpha-ketoisovalerate + NH3 + H2O2 | - |
? | |
| D-Val + H2O + O2 | 41% of the activity with D-Met | Acrostalagmus luteoalbus | alpha-ketoisovalerate + NH3 + H2O2 | - |
? | |
| D-Val + H2O + O2 | 62% of the activity with D-Ala | Fusarium oxysporum | alpha-ketoisovalerate + NH3 + H2O2 | - |
? | |
| D-Val + H2O + O2 | 8% of the activity with D-Ala | [Candida] boidinii | alpha-ketoisovalerate + NH3 + H2O2 | - |
? | |
| D-Val + H2O + O2 | 95% of the activity with D-Met | Rhodotorula toruloides | alpha-ketoisovalerate + NH3 + H2O2 | - |
? | |
| Gly + H2O + O2 | 15% of the activity with D-Ala | Candida parapsilosis | acetate + NH3 + H2O2 | - |
? | |
| Gly + H2O + O2 | 2% of the activity with D-Met | Acrostalagmus luteoalbus | acetate + NH3 + H2O2 | - |
? | |
| Gly + H2O + O2 | 3% of the activity with D-Met | Rhodotorula toruloides | acetate + NH3 + H2O2 | - |
? | |
| additional information | no activity with D-Trp, D-Tyr, D-Cys, D-Gln, D-Lys, D-Arg, D-His and D-Asp | [Candida] boidinii | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 40000 | Rhodotorula toruloides |
| ? | x * 39300 | Trigonopsis variabilis |
| ? | x * 39600 | Sus scrofa |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DAAO | - |
Sus scrofa |
| DAAO | - |
Rhodotorula toruloides |
| DAAO | - |
Candida parapsilosis |
| DAAO | - |
Fusarium oxysporum |
| DAAO | - |
Trigonopsis variabilis |
| DAAO | - |
Acrostalagmus luteoalbus |
| DAAO | - |
[Candida] boidinii |
| RgDAAO | - |
Rhodotorula toruloides |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 39 | - |
30 min, 50% decrease in activity | Sus scrofa |
| 44 | - |
30 min, 50% decrease in activity | Rhodotorula toruloides |
| 54 | - |
30 min, 50% decrease in activity | Trigonopsis variabilis |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 6 | 8 | stable | Sus scrofa |
| 6 | 8 | stable | Rhodotorula toruloides |
| 6 | 8 | stable | Trigonopsis variabilis |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | - |
Sus scrofa | |
| FAD | - |
Rhodotorula toruloides | |
| FAD | - |
Candida parapsilosis | |
| FAD | - |
Fusarium oxysporum | |
| FAD | - |
Trigonopsis variabilis | |
| FAD | - |
Acrostalagmus luteoalbus | |
| FAD | - |
[Candida] boidinii | |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Trigonopsis variabilis | - |
- |
4.9 |
| Rhodotorula toruloides | pI: 7.2, 7.4 and 7.8 | - |
6.9 |
| Sus scrofa | pI: 7.0 and 7.2 | - |
7 |
| Sus scrofa | pI: 7.0 and 7.2 | - |
7.1 |
| Rhodotorula toruloides | pI: 7.2, 7.4 and 7.8 | - |
7.1 |
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