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Literature summary for 1.4.3.2 extracted from

  • Nakano, M.; Tsutsumi, Y.; Danowski, T.S.
    Crystalline L-amino-acid oxidase from the soluble fraction of rat-kidney cells (1967), Biochim. Biophys. Acta, 139, 40-48.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
-
Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
Benzenearsonic acid
-
Rattus norvegicus
p-chloromercuribenzoate
-
Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Rattus norvegicus 5739
-
soluble
-
Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.98
-
-
Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-hydroxyisocaproic acid + H2O + O2
-
Rattus norvegicus 2-oxo-4-methylpentanoic acid + NH3 + H2O2
-
?
alpha-hydroxyvaleric acid + H2O + O2
-
Rattus norvegicus 2-oxopentanoic acid + NH3 + H2O2
-
?
hydroxyisovaleric acid + H2O + O2
-
Rattus norvegicus ? + NH3 + H2O2
-
?
L-amino acid + H2O + O2
-
Rattus norvegicus 2-oxo acid + NH3 + H2O2
-
?
L-lactic acid + H2O + O2
-
Rattus norvegicus pyruvate + NH3 + H2O2
-
?
L-leucine + H2O + O2
-
Rattus norvegicus 4-methyl-2-oxopentanoic acid + NH3 + H2O2
-
?
L-methionine + H2O + O2
-
Rattus norvegicus 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
?
L-phenylalanine + H2O + O2
-
Rattus norvegicus phenylpyruvate + NH3 + H2O2
-
?
L-tryptophan + H2O + O2
-
Rattus norvegicus indole-3-pyruvate + NH3 + H2O2
-
?
mandelic acid + H2O + O2
-
Rattus norvegicus phenylpyruvate + NH3 + H2O2
-
?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
45
-
5 min, stable Rattus norvegicus
51
-
5 min, inactivation above 51°C Rattus norvegicus
71
-
5 min, complete inactivation Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
FMN
-
Rattus norvegicus