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Literature summary for 1.4.3.2 extracted from
- Studies on L-amino-acid oxidase. I. Effects of pH and competitive inhibitors (1968), Biochim. Biophys. Acta, 167, 35-47.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| aromatic carboxylates | competitive | Crotalus adamanteus |  |
| benzoate | - |
Crotalus adamanteus | |
| D-mandelate | - |
Crotalus adamanteus | |
| L-Mandelate | - |
Crotalus adamanteus | |
| m-Aminobenzoate | - |
Crotalus adamanteus | |
| m-chlorobenzoate | - |
Crotalus adamanteus | |
| m-fluorobenzoate | - |
Crotalus adamanteus | |
| m-Hydroxybenzoate | - |
Crotalus adamanteus | |
| m-Nitrobenzoate | - |
Crotalus adamanteus | |
| Mandelate | - |
Crotalus adamanteus | |
| o-aminobenzoate | - |
Crotalus adamanteus | |
| o-chlorobenzoate | - |
Crotalus adamanteus | |
| o-fluorobenzoate | - |
Crotalus adamanteus | |
| o-hydroxybenzoate | - |
Crotalus adamanteus | |
| o-mercaptobenzoate | - |
Crotalus adamanteus | |
| o-Nitrobenzoate | - |
Crotalus adamanteus | |
| orthanilic acid | - |
Crotalus adamanteus | |
| p-Aminobenzoate | - |
Crotalus adamanteus | |
| p-Chlorobenzoate | - |
Crotalus adamanteus | |
| p-fluorobenzoate | - |
Crotalus adamanteus | |
| p-hydroxybenzoate | - |
Crotalus adamanteus | |
| p-nitrobenzoate | - |
Crotalus adamanteus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Crotalus adamanteus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| venom | - |
Crotalus adamanteus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-amino acid + H2O + O2 | - |
Crotalus adamanteus | 2-oxo acid + NH3 + H2O2 | - |
? | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.15 | - |
m-chlorobenzoate | - |
Crotalus adamanteus | |
| 0.34 | - |
m-Nitrobenzoate | - |
Crotalus adamanteus | |
| 0.37 | - |
m-fluorobenzoate | - |
Crotalus adamanteus | |
| 0.42 | - |
o-aminobenzoate | - |
Crotalus adamanteus | |
| 0.7 | - |
p-Chlorobenzoate | - |
Crotalus adamanteus | |
| 0.86 | - |
o-Nitrobenzoate | - |
Crotalus adamanteus | |
| 1 | - |
o-chlorobenzoate | - |
Crotalus adamanteus | |
| 1 | - |
o-mercaptobenzoate | - |
Crotalus adamanteus | |
| 1.2 | - |
orthanilic acid | - |
Crotalus adamanteus | |
| 1.3 | - |
p-fluorobenzoate | - |
Crotalus adamanteus | |
| 1.4 | - |
p-Aminobenzoate | - |
Crotalus adamanteus | |
| 1.4 | - |
o-fluorobenzoate | - |
Crotalus adamanteus | |
| 1.6 | - |
m-Aminobenzoate | - |
Crotalus adamanteus | |
| 1.7 | - |
benzoate | - |
Crotalus adamanteus | |
| 2.1 | - |
m-Hydroxybenzoate | - |
Crotalus adamanteus | |
| 2.2 | - |
o-hydroxybenzoate | - |
Crotalus adamanteus | |
| 2.3 | - |
p-hydroxybenzoate | - |
Crotalus adamanteus | |
| 2.3 | - |
p-nitrobenzoate | - |
Crotalus adamanteus | |
| 11 | - |
L-Mandelate | - |
Crotalus adamanteus | |
| 11 | - |
D-mandelate | - |
Crotalus adamanteus | |
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