Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.4.3.19 extracted from

  • Mörtl, M.; Diedrichs, K.; Welte, W.; Molla, G.; Motteran, L.; Andriolo, G.; Pilone, M.S.; Pollegioni, L.
    Structure-function correlation in glycine oxidase from Bacillus subtilis (2004), J. Biol. Chem., 279, 29718-29727.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging drop vapor diffusion method Bacillus subtilis

General Stability

General Stability Organism
tetrameric enzyme is strongly resistant to proteolysis, only the N-terminus is sensitive to proteases Bacillus subtilis
thiocyanate, up to 1 mM, decreases stability of the tetrameric enzyme in solution Bacillus subtilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Bacillus subtilis a general catabolic role of the enzyme on primary or secondary amines is excluded, because the expression of glycine oxidase is not inducible by Gly, sarcosine, or D-Ala as carbon or nitrogen source ?
-
?

Organism

Organism UniProt Comment Textmining
Bacillus subtilis O31616
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information a general catabolic role of the enzyme on primary or secondary amines is excluded, because the expression of glycine oxidase is not inducible by Gly, sarcosine, or D-Ala as carbon or nitrogen source Bacillus subtilis ?
-
?
sarcosine + H2O + O2
-
Bacillus subtilis glyoxylate + methylamine + H2O2
-
?

Subunits

Subunits Comment Organism
tetramer
-
Bacillus subtilis

pH Stability

pH Stability pH Stability Maximum Comment Organism
6.5 9.5 the tetrameric state of the enzyme is not affected by pH in the pH range 6.5-9.5 Bacillus subtilis

Cofactor

Cofactor Comment Organism Structure
FAD
-
Bacillus subtilis