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Literature summary for 1.4.1.4 extracted from

  • Alba-Lois, L.; Segal, C.; Rodarte, B.; Valdes-Lopez, V.; DeLuna, A.; Cardenas, R.
    NADP-glutamate dehydrogenase activity is increased under hyperosmotic conditions in the halotolerant yeast Debaryomyces hansenii (2004), Curr. Microbiol., 48, 68-72.
    View publication on PubMed
Search for more literature for 1.4.1.4

Inhibitors

Inhibitors Comment Organism Structure
KCl 500 mM, 80-90% inhibition, by high ionic strength Debaryomyces hansenii
NaCl 50 mM, 50% inhibition. 100 mM, about 60% inhibition. 500 mM, about 90% inhibition by high ionic strength Debaryomyces hansenii

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.021
-
 NADPH pH 8.0, 25°C Debaryomyces hansenii
2.2
-
 2-oxoglutarate pH 8.0, 25°C Debaryomyces hansenii
16
-
 NH3 pH 8.0, 25°C Debaryomyces hansenii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Debaryomyces hansenii enzyme synthesis is increased under hyperosmotic conditions in the halotolerant yeast ?
-
 ?
additional information Debaryomyces hansenii Y7426 enzyme synthesis is increased under hyperosmotic conditions in the halotolerant yeast ?
-
 ?

Organism

Organism UniProt Comment Textmining
Debaryomyces hansenii
-
-
-
Debaryomyces hansenii Y7426
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-oxoglutarate + NADPH + NH3
-
 Debaryomyces hansenii L-glutamate + NADP+ + H2O
-
 ?
2-oxoglutarate + NADPH + NH3
-
 Debaryomyces hansenii Y7426 L-glutamate + NADP+ + H2O
-
 ?
additional information enzyme synthesis is increased under hyperosmotic conditions in the halotolerant yeast Debaryomyces hansenii ?
-
 ?
additional information enzyme synthesis is increased under hyperosmotic conditions in the halotolerant yeast Debaryomyces hansenii Y7426 ?
-
 ?

Synonyms

Synonyms Comment Organism
NADP-GDH
-
 Debaryomyces hansenii
NADP-glutamate dehydrogenase
-
 Debaryomyces hansenii

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Debaryomyces hansenii