Inhibitors | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | NAD+ and NADP+ protect from inactivation in the presence of sodium glutarate | dogfish |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
300000 | 350000 | liver, sedimentation equilibrium | dogfish |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
dogfish | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+ | kinetic data suggest either a rapid-equilibrium random mechanism or a compulsory mechanism with binding sequence NH4+, NAD(P)H, 2-oxoglutarate | dogfish |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
dogfish | - |
Storage Stability | Organism |
---|---|
-15°, stable for several months | dogfish |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamate + H2O + NAD(P)+ | - |
dogfish | 2-oxoglutarate + NH3 + NAD(P)H | - |
r |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
dogfish | |
NADP+ | - |
dogfish |