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Literature summary for 1.4.1.3 extracted from

  • Langridge, W.H.R.; Komuniecki, P.; DeToma, F.J.
    Isolation and regulatory properties of two glutamate dehydrogenases from the cellular slime mold Dictyostelium discoideum (1977), Arch. Biochem. Biophys., 178, 581-587.
    View publication on PubMed
Search for more literature for 1.4.1.3

Activating Compound

Activating Compound Comment Organism Structure
ADP stimulation Dictyostelium discoideum
AMP 1 mM, reaction velocity increases 15fold at saturating NAD+ and glutamate levels Dictyostelium discoideum

Inhibitors

Inhibitors Comment Organism Structure
ATP strong inhibition Dictyostelium discoideum

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Dictyostelium discoideum 5739
-

Organism

Organism UniProt Comment Textmining
Dictyostelium discoideum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Dictyostelium discoideum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-glutamate + H2O + NAD(P)+
-
 Dictyostelium discoideum 2-oxoglutarate + NH3 + NAD(P)H
-
 r

Cofactor

Cofactor Comment Organism Structure
NAD+ 2 times higher reaction rate than with NADP+ Dictyostelium discoideum