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Literature summary for 1.4.1.2 extracted from

  • Gupta, P.; Gadre, R.
    Increase in NADH-glutamate dehydrogenase activity by mercury in excised bean leaf segments (2005), Indian J. Exp. Biol., 43, 824-828.
    View publication on PubMed
Search for more literature for 1.4.1.2

Activating Compound

Activating Compound Comment Organism Structure
NH4NO3 increases the NADH-GDH activity in the presence of Hg Phaseolus vulgaris

Application

Application Comment Organism
additional information possible role of enzyme under Hg-stress Phaseolus vulgaris

Inhibitors

Inhibitors Comment Organism Structure
Al3+ inhibits the enzyme activity in the absence of Hg Phaseolus vulgaris
glutamine reduces increase in GDH activity due to Hg Phaseolus vulgaris
glutathione reduces increase in GDH activity due to Hg Phaseolus vulgaris
additional information increase in GDH activity due to Hg remains unaffected by the supply of sucrose Phaseolus vulgaris

Metals/Ions

Metals/Ions Comment Organism Structure
Al3+ enhances increase in GDH activity due to Hg Phaseolus vulgaris
Hg2+ increases NADH-GDH activity substantially, however, specific activity of the enzyme decreases at lower concentration of Hg, and increases to lesser extent at higher concentration of Hg Phaseolus vulgaris

Organism

Organism UniProt Comment Textmining
Phaseolus vulgaris
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Phaseolus vulgaris
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
19.7
-
 in the absence of Hg and in the presence of 0.1 mM AlCl3 Phaseolus vulgaris
25
-
 in the presence of 0.001 mM Hg and in the presence of NH4NO3 Phaseolus vulgaris
26.7
-
 in the presence of 0.001 mM Hg Phaseolus vulgaris
34.2
-
 in the absence of Hg Phaseolus vulgaris
52.9
-
 in the absence of Hg and in the presence of 5 mM sucrose Phaseolus vulgaris
54.6
-
 in the presence of 0.01 mM Hg Phaseolus vulgaris
58.6
-
 in the absence of Hg and in the presence of 5 mM glutathione Phaseolus vulgaris
59.4
-
 in the absence of Hg and in the presence of 5 mM glutamine Phaseolus vulgaris
65.8
-
 in the absence of Hg and in the presence of NH4NO3 Phaseolus vulgaris
70.94
-
 in the presence of 0.1 mM Hg and in the presence of 5 mM glutathione Phaseolus vulgaris
72
-
 in the presence of 0.01 mM Hg and in the presence of NH4NO3 Phaseolus vulgaris
119.5
-
 in the presence of 0.1 mM Hg Phaseolus vulgaris
170.6
-
 in the presence of 0.1 mM Hg and in the presence of 5 mM glutamine Phaseolus vulgaris
171.4
-
 in the presence of 0.1 mM Hg and in the presence of 0.1 mM AlCl3 Phaseolus vulgaris
243.4
-
 in the presence of 0.1 mM Hg and in the presence of NH4NO3 Phaseolus vulgaris
328.2
-
 in the presence of 0.1 mM Hg and in the presence of 5 mM sucrose Phaseolus vulgaris

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-oxoglutarate + NH3 + NADH
-
 Phaseolus vulgaris L-glutamate + H2O + NAD+
-
 r

Synonyms

Synonyms Comment Organism
NADH-GDH
-
 Phaseolus vulgaris
NADH-glutamate dehydrogenase
-
 Phaseolus vulgaris

Cofactor

Cofactor Comment Organism Structure
NADH gradual increase in enzyme activity with increasing concentrations of NADH in preparations with 0.1 mM Hg or without Hg Phaseolus vulgaris