Literature summary for 1.4.1.16 extracted from

Misono, H.; Nagasaki, S.; Soda, K.
meso-alpha,epsilon-Diaminopimelate D-dehydrogenase: sulfhydryl group modification (1981), Agric. Biol. Chem., 45, 1455-1460.

No PubMed abstract available

Search for more literature for 1.4.1.16

Inhibitors

Inhibitors	Comment	Organism	Structure
4,4'-Dithiopyridine	complete inactivation	Lysinibacillus sphaericus
5,5'-dithiobis(2-nitrobenzoate)	complete inactivation	Lysinibacillus sphaericus
HgCl2	-	Lysinibacillus sphaericus
iodoacetate	complete inactivation	Lysinibacillus sphaericus
N-ethylmaleimide	complete inactivation	Lysinibacillus sphaericus
p-chloromercuribenzoate	complete inactivation	Lysinibacillus sphaericus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-2-amino-6-oxoheptanedioate + NH3 + NADPH	Lysinibacillus sphaericus	-	meso-2,6-diaminoheptanedioate + H2O + NADP+	-	r

Organism

Organism	UniProt	Comment	Textmining
Lysinibacillus sphaericus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H	-	Lysinibacillus sphaericus	meso-2,6-diaminoheptanedioate + H2O + NAD(P)+	-	r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH	-	Lysinibacillus sphaericus	meso-2,6-diaminoheptanedioate + H2O + NADP+	-	r

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Lysinibacillus sphaericus

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Release 2023.1 (January 2023)