Literature summary for 1.4.1.1 extracted from

Keradjopoulos, D.; Holldorf, A.W.
Thermophilic character of enzymes from extreme halophilic bacteria (1977), FEMS Microbiol. Lett., 1, 179-182.

No PubMed abstract available

Search for more literature for 1.4.1.1

Inhibitors

Inhibitors	Comment	Organism	Structure
PCMB	-	Bacillus subtilis
PCMB	reversed by L-Cys	Halobacterium salinarum

Metals/Ions

Metals/Ions	Comment	Organism	Structure
NaCl	optimal concentration: 4.3 M	Halobacterium salinarum
NaCl	optimal concentration: 4.0 M	Halobacterium salinarum

Organism

Organism	UniProt	Comment	Textmining
Bacillus cereus	-	-	-
Bacillus cereus T	-	-	-
Bacillus subtilis	-	-	-
Halobacterium salinarum	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-Ala + H2O + NAD+	-	Bacillus subtilis	pyruvate + NH3 + NADH	-	r
L-Ala + H2O + NAD+	-	Halobacterium salinarum	pyruvate + NH3 + NADH	-	r
L-Ala + H2O + NAD+	-	Bacillus cereus	pyruvate + NH3 + NADH	-	r
L-Ala + H2O + NAD+	-	Bacillus cereus T	pyruvate + NH3 + NADH	-	r

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
65	-	-	Halobacterium salinarum
65	-	3.5 NaCl	Halobacterium salinarum

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
8.5	-	reductive amination of pyruvate	Bacillus subtilis
9	-	-	Halobacterium salinarum

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Bacillus subtilis
NAD+	-	Halobacterium salinarum
NAD+	-	Bacillus cereus
NADH	-	Bacillus subtilis
NADH	-	Halobacterium salinarum
NADH	-	Bacillus cereus

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Release 2023.1 (January 2023)