Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(4-[4-(4-bromophenoxy)benzoyl]phenyl)acetic acid | pH 5.5, 55% inhibition at 0.01 mM, pH 6.6, 59% inhibition at 0.01 mM | Rattus norvegicus | |
3-[4-(4-phenoxybenzoyl)phenyl]acrylic acid | pH 5.5, isoform 2, 50% inhibition at 0.00047 mM, not inhibitory to isoform 1 | Homo sapiens | |
3-[4-(4-phenoxybenzoyl)phenyl]acrylic acid | pH 5.5, 63% inhibition at 0.01 mM, pH 6.6, 61% inhibition at 0.01 mM | Rattus norvegicus | |
4-(4-([2,6-bis(trifluoromethyl)benzyl]oxy)benzoyl)benzoic acid | pH 5.5, 29% inhibition at 0.01 mM, pH 6.6, 69% inhibition at 0.01 mM | Rattus norvegicus | |
4-(4-phenoxybenzoyl)benzoic acid | pH 5.5, isoform 2, 50% inhibition at 0.000053 mM, not inhibitory to isoform 1 | Homo sapiens | |
4-(4-phenoxybenzoyl)benzoic acid | pH 5.5, 33% inhibition at 0.01 mM, pH 6.6, 53% inhibition at 0.01 mM | Rattus norvegicus | |
4-(4-[[2,6-bis(trifluoromethyl)benzyl]oxy]benzoyl)benzoic acid | pH 5.5, isoform 2, 50% inhibition at 0.000113 mM, isoform 1, 12% inhibition at 0.01 mM | Homo sapiens | |
4-[3-(benzyloxy)benzoyl]benzoic acid | pH 5.5, isoform 2, 50% inhibition at 0.000131 mM, not inhibitory to isoform 1 | Homo sapiens | |
4-[3-(benzyloxy)benzoyl]benzoic acid | pH 5.5, 55% inhibition at 0.01 mM, pH 6.6, 35% inhibition at 0.01 mM | Rattus norvegicus | |
4-[4-(benzyloxy)benzoyl]benzoic acid | pH 5.5, isoform 2, 50% inhibition at 0.000119 mM, not inhibitory to isoform 1 | Homo sapiens | |
4-[4-(benzyloxy)benzoyl]benzoic acid | pH 5.5, 0.01 mM, 45% inhibition at 0.01 mM, pH 6.6, 64% inhibition at 0.01 mM | Rattus norvegicus | |
finasteride | pH 5.5, isoform 2, 50% inhibition at 0.000005 mM, isoform 1, 50% inhibition at 0.051 mM | Homo sapiens | |
finasteride | pH 5.5, 50% inhibition at 0.000011 mM, pH 6.6, 50% inhibition at 0.00001 mM | Rattus norvegicus | |
[3-fluoro-4-(4-phenoxybenzoyl)phenyl]acetic acid | pH 5.5, isoform 2, 50% inhibition at 0.000045 mM, not inhibitory to isoform 1 | Homo sapiens | |
[3-fluoro-4-(4-phenoxybenzoyl)phenyl]acetic acid | pH 5.5, 73% inhibition at 0.01 mM, pH 6.6, 57% inhibition at 0.01 mM | Rattus norvegicus | |
[3-methyl-4-(4-phenoxybenzoyl)phenyl]acetic acid | pH 5.5, isoform 2, 50% inhibition at 0.000027 mM, not inhibitory to isoform 1 | Homo sapiens | |
[3-methyl-4-(4-phenoxybenzoyl)phenyl]acetic acid | pH 5.5, 78% inhibition at 0.01 mM, pH 6.6, 50% inhibition at 0.00145 mM | Rattus norvegicus | |
[4-(4-phenoxybenzoyl)phenyl]acetic acid | pH 5.5, isoform 2, 50% inhibition at 0.000023 mM, not inhibitory to isoform 1 | Homo sapiens | |
[4-(4-phenoxybenzoyl)phenyl]acetic acid | pH 5.5, 77% inhibition at 0.01 mM, pH 6.6, 42% inhibition at 0.01 mM | Rattus norvegicus | |
[4-[4-(4-bromophenoxy)benzoyl]phenyl]acetic acid | pH 5.5, isoform 2, 50% inhibition at 0.000005 mM, not inhibitory to isoform 1 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isoforms 1 and 2 | - |
Rattus norvegicus | - |
isoforms 1 and 2 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
prostate | - |
Homo sapiens | - |
prostate gland | ventral prostate | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-androstene-3,17-dione + acceptor | - |
Homo sapiens | 1,4-androstadiene-3,17-dione + reduced reduced acceptor | - |
? | |
testosterone + reduced acceptor | - |
Homo sapiens | 5alpha-dihydrotestosterone + acceptor | - |
? | |
testosterone + reduced acceptor | - |
Rattus norvegicus | 5alpha-dihydrotestosterone + acceptor | - |
? |