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Literature summary for 1.3.99.4 extracted from

  • Aries, V.C.; Goddard, P.; Hill, M.J.
    Degradation of steroids by intestinal bacteria. III. 3-Oxo-5beta-steroid DELTA1-dehydrogenase and 3-oxo-5beta-steroid DELTA4-dehydrogenase (1971), Biochim. Biophys. Acta, 248, 482-488.
No PubMed abstract available
Search for more literature for 1.3.99.4

Organism

Organism UniProt Comment Textmining
Clostridium paraputrificum
-
 3-oxo-5beta-steroid DELTA1-dehydrogenase is active only on 5-beta-steroids
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-oxo-5beta-cholan-24-oic acid + acceptor
-
 Clostridium paraputrificum ? + reduced acceptor
-
 ?
5beta-androstan-3,17-dione + acceptor
-
 Clostridium paraputrificum 5beta-androst-1-en-3,17-dione + reduced acceptor
-
 ?
additional information acceptor: phenazine methosulfate Clostridium paraputrificum ?
-
 ?
additional information acceptor: O2 Clostridium paraputrificum ?
-
 ?
additional information 3-oxo-5beta-steroid DELTA1-dehydrogenase is active only on 5beta-steroids Clostridium paraputrificum ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8 9 3-oxo-5beta-steroid DELTA1-dehydrogenase is active only on 5beta-steroids Clostridium paraputrificum