Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli C43 (DE3) cells | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
complexed with myristoyl-CoA, hanging drop vapour diffusion method, in 0.1 M HEPES, pH 7.5, 17.6% polyethylene glycol 2000, 0.047 M MgCl2, and 5% glycerol | Homo sapiens |
in complex with myristoyl-CoA, sitting drop vapour diffusion method, in 0.1 M HEPES, pH 7.5, 17.6% polyethylene glycol 2000, 0.047 M MgCl2, and 5% glycerol | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial membrane | - |
Homo sapiens | 31966 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
ammonium sulfate precipitation and DEAE-Sepharose Fast Flow column chromatography | Homo sapiens |
DEAE-Sepharose Fast Flow column chromatography and SP-Sepharose Fast Flow column chromatography | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
myristoyl-CoA + acceptor | - |
Homo sapiens | 2-tetradecenoyl-CoA + reduced acceptor | - |
? | |
myristoyl-CoA + acceptor | - |
Homo sapiens | trans(2)-tetradecenoyl-CoA + reduced acceptor | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | x-ray crystallography | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
very-long-chain acyl-CoA dehydrogenase | - |
Homo sapiens |
very-long-chain acyl-CoA dehydrogenase | most active with C14 substrates | Homo sapiens |
VLCAD | - |
Homo sapiens |
VLCAD | optimal chain length specificity for fatty acyl-CoAs having 16 carbons in length | Homo sapiens |