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Literature summary for 1.3.8.7 extracted from

  • Chalmers, R.A.; English, N.
    Fatty acid oxidation in cultured skin fibroblasts from patients with inherited disorders of fatty acid metabolism: studies on the specificity of acyl-CoA dehydrogenases (1987), Biochem. Soc. Trans., 15, 489-491.
No PubMed abstract available
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + electron transfer flavoprotein Homo sapiens first step in beta-oxidation of fatty acids 2,3-dehydroacyl-CoA + reduced electron transfer flavoprotein
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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 skin fibroblast cell lines from healthy subjects and from patients with medium-chain, long-chain and with multiple-chain acyl-CoA dehydrogenase deficiency
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Source Tissue

Source Tissue Comment Organism Textmining
skin fibroblast
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 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + acceptor specific for chain lengths C6-C8 Homo sapiens 2,3-dehydroacyl-CoA + reduced acceptor
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 ?
acyl-CoA + electron transfer flavoprotein first step in beta-oxidation of fatty acids Homo sapiens 2,3-dehydroacyl-CoA + reduced electron transfer flavoprotein
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 ?
n-octanoyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol fibroblast medium-chain acyl-CoA dehydrogenase is specific towards C6-C8 acyl-CoA esters Homo sapiens 2-octenoyl-CoA + reduced acceptor
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 ?