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Literature summary for 1.3.8.6 extracted from

  • Besrat, A.; Polan, C.E.; Henderson, L.M.
    Mammalian metabolism of glutaric acid (1969), J. Biol. Chem., 244, 1461-1467.
    View publication on PubMed
Search for more literature for 1.3.8.6

Activating Compound

Activating Compound Comment Organism Structure
FAD exogenous Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
Co2+
-
 Bos taurus
Cu2+
-
 Bos taurus
glutaconyl-CoA
-
 Bos taurus
p-chloromercuribenzoate
-
 Bos taurus
Zn2+
-
 Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0012 0.01 glutaryl-CoA
-
 Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Bos taurus 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
200000
-
 gel filtration Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Bos taurus
-
liver
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutaryl-CoA + acceptor acceptors: electron-transfer flavoprotein, phenylmethylsulfonyl fluoride, 2,6-dichlorophenolindophenol, phenazine methosulfate, methylene blue Bos taurus crotonyl-CoA + CO2 + reduced acceptor
-
 ?
glutarylpantetheine + acceptor
-
 Bos taurus crotonylpantetheine + reduced acceptor
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5 8 glutaryl-CoA + methylene blue Bos taurus

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Bos taurus