Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.3.5.2 extracted from

  • Zameitat, E.; Freymark, G.; Dietz, C.D.; Loeffler, M.; Boelker, M.
    Functional expression of human dihydroorotate dehydrogenase (DHODH) in pyr4 mutants of Ustilago maydis allows target validation of DHODH inhibitors in vivo (2007), Appl. Environ. Microbiol., 73, 3371-3379.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in pyr4 mutants of Ustilago maydis Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
brequinar sensitive to brequinar at a 0.01 mM concentration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q02127
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
99
-
with L-dihydroorotate and 2,6-dichloroindophenol as substrates, at 30°C Homo sapiens

Synonyms

Synonyms Comment Organism
DHODH
-
Homo sapiens