Literature summary for 1.3.5.1 extracted from

Papaspyrou, K.; Rossmann, H.; Fottner, C.; Weber, M.M.; Mann, W.; Lackner, K.J.; Helling, K.
Malignant paraganglioma caused by a novel germline mutation of the succinate dehydrogenase D-gene - a case report (2008), Head Neck, 30, 964-969.

Search for more literature for 1.3.5.1

Cloned(Commentary)

Cloned (Comment)	Organism
genes SDHB, SDHC, and SDHD, DNA and amino acid sequence determination and analysis, genotyping	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
R17X	naturally occuring mutation in the SDHD gene of a 29-year-old man showing metastases in both lungs and the liver, but no increased hormone production by the tumor, phenotype, overview	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	approximately 10% to 15% of paragangliomas are caused by mutations in the succinate dehydrogenase genes SDHB, SDHC, or SDHD	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	approximately 10% to 15% of paragangliomas are caused by mutations in the succinate dehydrogenase genes SDHB, SDHC, or SDHD	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
SDH	-	Homo sapiens
succinate dehydrogenase	-	Homo sapiens

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Release 2023.1 (January 2023)