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Literature summary for 1.3.5.1 extracted from

  • Pettenuzzo, L.F.; Ferreira, G.d.a.C.; Schmidt, A.L.; Dutra-Filho, C.S.; Wyse, A.T.; Wajner, M.
    Differential inhibitory effects of methylmalonic acid on respiratory chain complex activities in rat tissues (2006), Int. J. Dev. Neurosci., 24, 45-52.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information 15-20% inhibition of complex II activity in striatum and hippocampus by methylmalonic acid at low concentrations of sucinate in the medium, but not in the peripheral tissue. the inhibitory property only occurs after exposing brain homogenates for at least 10 min with the acid, suggesting that this inhibition is mediated by indirect mechanisms Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
corpus striatum 15-20% inhibition of complex II activity in striatum and hippocampus by methylmalonic acid at low concentrations of sucinate in the medium, but not in the peripheral tissue. the inhibitory property only occurs after exposing brain homogenates for at least 10 min with the acid, suggesting that this inhibition is mediated by indirect mechanisms Rattus norvegicus
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hippocampus 15-20% inhibition of complex II activity in striatum and hippocampus by methylmalonic acid at low concentrations of sucinate in the medium, but not in the peripheral tissue. the inhibitory property only occurs after exposing brain homogenates for at least 10 min with the acid, suggesting that this inhibition is mediated by indirect mechanisms Rattus norvegicus
-

Synonyms

Synonyms Comment Organism
complex II
-
Rattus norvegicus