Protein Variants | Comment | Organism |
---|---|---|
F204L | CG400549-resistant mutant | Staphylococcus aureus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-(3-amino-2-methylbenzyl)-4-(2-thiophen-2-ylethoxy)pyridin-2(1H)-one | CG400549, potent in vitro and in vivo activity against FabI | Staphylococcus aureus | |
triclosan | - |
Staphylococcus aureus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | - |
- |
- |
Staphylococcus aureus RN4220 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-[acyl-carrier protein] + NAD+ | - |
Staphylococcus aureus | trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+ | - |
? | |
acyl-[acyl-carrier protein] + NAD+ | - |
Staphylococcus aureus RN4220 | trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
enoyl-ACP reductase | - |
Staphylococcus aureus |
FabI | - |
Staphylococcus aureus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Staphylococcus aureus |