Literature summary for 1.3.1.8 extracted from

Rennison, J.H.; McElfresh, T.A.; Okere, I.C.; Patel, H.V.; Foster, A.B.; Patel, K.K.; Stoll, M.S.; Minkler, P.E.; Fujioka, H.; Hoit, B.D.; Young, M.E.; Hoppel, C.L.; Chandler, M.P.
Enhanced acyl-CoA dehydrogenase activity is associated with improved mitochondrial and contractile function in heart failure (2008), Cardiovasc. Res., 79, 331-340.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Rattus norvegicus	5739	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
(2E)-hexadec-2-enoyl-CoA + NADPH	Rattus norvegicus	-	palmitoyl-CoA + NADP+	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
heart	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(2E)-hexadec-2-enoyl-CoA + NADPH	-	Rattus norvegicus	palmitoyl-CoA + NADP+	-	?
2-trans-octenoyl-CoA + NADPH	-	Rattus norvegicus	octanoyl-CoA + NADP+	-	?
crotonyl-CoA + NADPH	-	Rattus norvegicus	butyryl-CoA + NADP+	-	?

Synonyms

Synonyms	Comment	Organism
MCAD	-	Rattus norvegicus
medium-chain acyl-CoA dehydrogenase	-	Rattus norvegicus

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Rattus norvegicus

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Release 2023.1 (January 2023)