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Literature summary for 1.3.1.72 extracted from
- 3beta-Hydroxysteroid-DELTA24 reductase is a hydrogen peroxide scavenger, protecting cells from oxidative stress-induced apoptosis (2008), Endocrinology, 149, 3267-3273.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Mus musculus embryonic fibroblasts and PC-12 cells infected with adenovirus | Mus musculus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum | - |
Mus musculus | 5783 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5alpha-cholesta-7,24-dien-3beta-ol + NADPH | - |
Mus musculus | 5alpha-cholest-7-en-3beta-ol + NADP+ | - |
? |  |
| additional information | intracellular generation of reactive oxygen species in response to H2O2 is diminished in the presence of DHCR24, suggesting a reactive oxygen species-scavenging activity of DHCR24 | Mus musculus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 3beta-hydroxysteroid-DELTA24 reductase | - |
Mus musculus |
| DHCR24 | - |
Mus musculus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Mus musculus | |
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Release 2023.1 (January 2023)
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