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Literature summary for 1.3.1.70 extracted from

  • Yamashita, Y.; Nishibori, M.; Terada, T.; Isobe, N.; Shimada, M.
    Gonadotropin-induced DELTA14-reductase and DELTA7-reductase gene expression in cumulus cells during meiotic resumption of porcine oocytes (2005), Endocrinology, 146, 186-194.
    View publication on PubMed
Search for more literature for 1.3.1.70

Activating Compound

Activating Compound Comment Organism Structure
additional information enzyme expression is induced by gonadotropin, overview Sus scrofa

Inhibitors

Inhibitors Comment Organism Structure
AY9944-A-7 enzyme-specific inhibitor, leads to apoptosis in vivo at high concentrations in cumulus cells of oocytes Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
follicular fluid meiosis-activating sterol + NADPH Sus scrofa
-
 testicular meiosis-activating sterol + NADP+
-
 ?
additional information Sus scrofa enzyme is involved in de novo synthesis of progesterone from lanosterol via cholesterol, pathway overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information enzyme expression is induced by gonadotropin Sus scrofa
-
oocyte
-
 Sus scrofa
-
ovarian cumulus cell during meiotic resumption of oocytes Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
follicular fluid meiosis-activating sterol + NADPH
-
 Sus scrofa testicular meiosis-activating sterol + NADP+
-
 ?
additional information enzyme is involved in de novo synthesis of progesterone from lanosterol via cholesterol, pathway overview Sus scrofa ?
-
 ?

Synonyms

Synonyms Comment Organism
DELTA14-reductase
-
 Sus scrofa

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Sus scrofa