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Literature summary for 1.3.1.6 extracted from

  • Weingarten, R.A.; Taveirne, M.E.; Olson, J.W.
    The dual-functioning fumarate reductase is the sole succinate:quinone reductase in Campylobacter jejuni and is required for full host colonization (2009), J. Bacteriol., 191, 5293-5300.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.3.1.6

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
succinate + NAD+ Campylobacter jejuni
-
 fumarate + NADH + H+
-
 r
succinate + NAD+ Campylobacter jejuni NCTC 11168
-
 fumarate + NADH + H+
-
 r

Organism

Organism UniProt Comment Textmining
Campylobacter jejuni Q0PBA0 fumarate reductase iron-sulfur protein; gene Cj0410 or frdB
-
Campylobacter jejuni Q0PBA1 fumarate reductase subunit A; gene Cj0409 or frdA
-
Campylobacter jejuni Q0PBA2 fumarate reductase subunit B; gene Cj0408 or frdC
-
Campylobacter jejuni NCTC 11168 Q0PBA0 fumarate reductase iron-sulfur protein; gene Cj0410 or frdB
-
Campylobacter jejuni NCTC 11168 Q0PBA1 fumarate reductase subunit A; gene Cj0409 or frdA
-
Campylobacter jejuni NCTC 11168 Q0PBA2 fumarate reductase subunit B; gene Cj0408 or frdC
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information FRD activity is measured as the change in absorbance produced by the oxidation of reduced benzyl viologen Campylobacter jejuni ?
-
 ?
additional information FRD activity is measured as the change in absorbance produced by the oxidation of reduced benzyl viologen Campylobacter jejuni NCTC 11168 ?
-
 ?
succinate + NAD+
-
 Campylobacter jejuni fumarate + NADH + H+
-
 r
succinate + NAD+
-
 Campylobacter jejuni NCTC 11168 fumarate + NADH + H+
-
 r

Synonyms

Synonyms Comment Organism
fumarate reductase
-
 Campylobacter jejuni

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Campylobacter jejuni
NADH
-
 Campylobacter jejuni

General Information

General Information Comment Organism
additional information the frdA::cat strain is completely deficient in succinate dehydrogenase activity in vitro and is unable to perform whole-cell succinate-dependent respiration. The mutant strain is also unable to grow with the characteristic wild-type biphasic growth pattern and exhibits only the first growth phase, which is marked by the consumption of aspartate, serine, and associated organic acids Campylobacter jejuni