Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli as glutathione-S-transferase fusion protein | Cavia porcellus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0085 | - |
15-keto-prostaglandin E2 | - |
Cavia porcellus | |
0.093 | - |
(5S,12R)-dihydroxy-(6E,8Z,10Z,14E)-eicosatetraenoic acid | - |
Cavia porcellus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant enzyme | Cavia porcellus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Cavia porcellus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(5S,12R)-dihydroxy-(6E,8Z,10Z,14E)-eicosatetraenoic acid + NADH | 15-keto-prostaglandin-13-reductase activity is 200fold higher than leukotrien B4-12hydroxydehydrogenase activity | Cavia porcellus | ? | - |
? | |
11-hydroxy-9,15-dioxoprosta-5,13-dien-1-oic acid + NAD(P)H | - |
Cavia porcellus | 11-hydroxy-9,15-dioxoprosta-5-en-1-oic acid + NAD(P)+ | - |
? | |
15-ketoprostaglandin E2 + NADH + H+ | - |
Cavia porcellus | 13,14-dihydro-15-ketoprostaglandin E2 + NAD+ | - |
r |
Synonyms | Comment | Organism |
---|---|---|
leukotriene B4 12-hydroxydehydrogenase/15-ketoprostaglandin 13-reductase | - |
Cavia porcellus |