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Literature summary for 1.3.1.45 extracted from

  • Zhu, Q.L.; Guo, T.Y.; Sui, S.Z.; Liu, G.D.; Lei, X.H.; Luo, L.L.; Li, M.Y.
    Molecular cloning and characterization of a novel isoflavone reductase-like gene (FcIRL) from high flavonoids-producing callus of Fagopyrum cymosum (2009), Yao Xue Xue Bao, 44, 809-819.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
cloning of full-length FcIRL, DNA and amino acid sequence determination and analysis, sequence comparison and phylogenetic analysis, overview Fagopyrum cymosum

Inhibitors

Inhibitors Comment Organism Structure
additional information the enzyme sequence contains a conserved NmrA, nitrogen metabolite repression regulator, domain, V6-N244 Fagopyrum cymosum

Organism

Organism UniProt Comment Textmining
Fagopyrum cymosum A7Y232
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein the enzyme sequence contains one conserved glycosylation site at N214 Fagopyrum cymosum
additional information the enzyme sequence contains an N-terminal acetylation site M1-K5 Fagopyrum cymosum
phosphoprotein the enzyme sequence contains multi-phosphorylation sites Fagopyrum cymosum

Source Tissue

Source Tissue Comment Organism Textmining
callus
-
 Fagopyrum cymosum
-

Synonyms

Synonyms Comment Organism
IRL
-
 Fagopyrum cymosum
isoflavone reductase
-
 Fagopyrum cymosum
More FcIRL belongs to the class of pinoresinol-lariciresinol reductase, PRL, functioning in the biosynthesis of 8,8'-linked lignans Fagopyrum cymosum

Cofactor

Cofactor Comment Organism Structure
NADPH the enzyme sequence contains a NADPH-binding motif, G10GTG13YIG16, in the N-terminal region Fagopyrum cymosum

General Information

General Information Comment Organism
metabolism FcIRL belongs to the class of pinoresinol-lariciresinol reductase, PRL, functioning in the biosynthesis of 8,8'-linked lignans, with function in catalyzing reduction of pinoresinol and lariciresinol into secoisolariciresinol, and medicinal secondary metabolism and resistance in Fagopyrum cymosum Fagopyrum cymosum