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Literature summary for 1.3.1.24 extracted from

  • Zhang, M.; Song, S.; Yi, Z.; Zhao, X.; Fu, L.; Wang, L.; Ma, C.; Mao, M.; Xing, Y.; Zhu, D.
    Human biliverdin reductase promotes EMT through the ERK1/2 signal pathway in breast cancer (2016), Eur. J. Pharmacol., 788, 45-53.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Homo sapiens 5737
-
nucleus
-
Homo sapiens 5634
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
37000
-
x * 37000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
biliverdin + NADH + H+ Homo sapiens
-
bilirubin + NAD+
-
r
biliverdin + NADPH + H+ Homo sapiens
-
bilirubin + NADP+
-
r

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast epithelial cell
-
Homo sapiens
-
MCF-10A cell
-
Homo sapiens
-
MCF-7 cell
-
Homo sapiens
-
MDA-MB-231 cell
-
Homo sapiens
-
T-47D cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
biliverdin + NADH + H+
-
Homo sapiens bilirubin + NAD+
-
r
biliverdin + NADPH + H+
-
Homo sapiens bilirubin + NADP+
-
r

Subunits

Subunits Comment Organism
? x * 37000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
BVR
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NADH
-
Homo sapiens
NADPH
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens enzyme expression is up-regulated in breast cancer cells up