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Literature summary for 1.3.1.24 extracted from
- Biliverdin inhibits activation of NF-kappaB: reversal of inhibition by human biliverdin reductase (2007), Int. J. Cancer, 121, 2567-2574.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Tumor necrosis factor alpha | - |
Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in HEK293A and MCF-7 cells | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| nucleus | - |
Homo sapiens | 5634 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| biliverdin + NAD(P)H + H+ | - |
Homo sapiens | bilirubin + NAD(P)+ | - |
? |  |
| additional information | BVR is likely to affect the activation of nuclear factor kappaB both in its capacity as a reductase as well as a kinase | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BVR | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD(P)H | - |
Homo sapiens | |
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