Inhibitors | Comment | Organism | Structure |
---|---|---|---|
dutasteride | 0.5 mg/day, dual 5alpha-reductase inhibitor | Homo sapiens | |
finasteride | 5.0 mg/day, effective inhibitor of type 2 5alpha-reductase | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
testosterone + NADPH + H+ | - |
Homo sapiens | 5alpha-dihydrotestosterone + NADP+ + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
5alpha-reductase type 1 | the isoenzyme predominates in the reproductive tissues, genital skin, and epididymis | Homo sapiens |
5alpha-reductase type 2 | the isoenzyme is predominantly found in the skin, liver, and testes | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens |