Activating Compound | Comment | Organism | Structure |
---|---|---|---|
sulpiride | 40 mg/kg doses induce mRNA expression of 5alphaR1 and 5alpha-R2 | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P24008 | isozyme 5alpha-R1 | - |
Rattus norvegicus | P31214 | isozyme 5alpha-R2 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
prostate gland | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
testosterone + NADPH + H+ | - |
Rattus norvegicus | 5alpha-dihydrotestosterone + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
5alpha-R1 | isozyme | Rattus norvegicus |
5alpha-R2 | isozyme | Rattus norvegicus |
steroid 5alpha-reductase | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Rattus norvegicus |