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Literature summary for 1.3.1.22 extracted from
- Partial characterization of the nuclear reduced nicotinamide adenine dinucleotide phosphate: DELTA 4-3-ketosteroid 5alpha-oxidoreductase of rat prostate (1971), J. Biol. Chem., 246, 2584-2593.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| epididymis | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cholest-4-en-3-one + NADPH | - |
Rattus norvegicus | 5-alpha-cholestan-3-one + NADP+ | - |
? |  |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| additional information | NADH: no activity | Rattus norvegicus | |
| additional information | absolute requirement for NADPH in rat epididymis | Rattus norvegicus | |
| NADPH | absolute requirement for NADPH | Rattus norvegicus | |
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Release 2023.1 (January 2023)
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