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Literature summary for 1.3.1.21 extracted from

  • Trzaskos, J.M.; Gaylor, J.L.
    Cytosolic modulators of activities of microsomal enzymes of cholesterol biosynthesis. Purification and characterization of a non-specific lipid-transfer protein (1983), Biochim. Biophys. Acta, 751, 52-65.
    View publication on PubMed
Search for more literature for 1.3.1.21

Activating Compound

Activating Compound Comment Organism Structure
Lipid transfer protein cytosolic, activity enhancement which is inhibited by addition of Tween 80, probably identical with sterol carrier protein Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome cytosolic lipid transfer protein stimulates membrane bound enzyme activity Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cholesta-5,7-dien-3-beta-ol + NADPH Rattus norvegicus
-
 cholesterol + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cholesta-5,7-dien-3-beta-ol + NADPH
-
 Rattus norvegicus cholesterol + NADP+
-
 ?
cholesta-5,7-dien-3beta-ol + NADPH
-
 Rattus norvegicus cholesterol + NADP+
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.8
-
 assay at Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Rattus norvegicus