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Literature summary for 1.3.1.21 extracted from

  • Banik, N.L.; Davison, A.N.
    Exchange of sterols between myelin and other membranes of developing rat brain (1971), Biochem. J., 122, 751-758.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.3.1.21

Inhibitors

Inhibitors Comment Organism Structure
7-dehydrocholesterol depending on age of rats Rattus norvegicus
trans-1,4-Bis-(2-chlorobenzylaminomethyl)cyclohexane dihydrochloride i.e. AY-9944, hypercholesterolaemic drug Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-
additional information subcellular localization Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cholesta-5,7-dien-3-beta-ol + NADPH Rattus norvegicus cholesterol formation outside myelin sheath cholesterol + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
myelin 15-20% of total activiy in brain, lipid exchange between microsomes and myelin Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cholesta-5,7-dien-3-beta-ol + NADPH cholesterol formation outside myelin sheath Rattus norvegicus cholesterol + NADP+
-
 ?
cholesta-5,7-dien-3beta-ol + NADPH
-
 Rattus norvegicus cholesterol + NADP+
-
 ?