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Literature summary for 1.3.1.13 extracted from
- Aromatic metabolism in plants I. A study of the prephenate dehydrogenase from bean plants (1966), Biochim. Biophys. Acta, 115, 65-72.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4-chloromercuriphenylsulfonic acid | - |
Phaseolus vulgaris |  |
| N-ethylmaleimide | - |
Phaseolus vulgaris | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.077 | - |
NADP+ | - |
Phaseolus vulgaris | |
| 0.079 | - |
NADP+ | - |
Phaseolus vulgaris | |
| 0.13 | - |
prephenate | - |
Phaseolus vulgaris | |
| 0.18 | - |
prephenate | - |
Phaseolus vulgaris | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| prephenate + NADP+ | Phaseolus vulgaris | - |
4-hydroxyphenylpyruvate + CO2 + NADPH | - |
? | |
| prephenate + NADP+ | Vicia faba | - |
4-hydroxyphenylpyruvate + CO2 + NADPH | - |
? | |
| prephenate + NADP+ | Klebsiella aerogenes | - |
4-hydroxyphenylpyruvate + CO2 + NADPH | - |
? | |
| prephenate + NADP+ | Vigna radiata | - |
4-hydroxyphenylpyruvate + CO2 + NADPH | - |
? | |
| prephenate + NADP+ | Phaseolus coccineus | - |
4-hydroxyphenylpyruvate + CO2 + NADPH | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Klebsiella aerogenes | - |
- |
- |
| no activity in Beta vulgaris subsp. vulgaris | - |
red beet, Beta vulgaris ssp. var. conditiva, Beta vulgaris ssp. vulgaris var. rubra | - |
| no activity in Oryza sativa | - |
rice | - |
| no activity in Pisum sativum | - |
pea | - |
| no activity in Triticum aestivum | - |
wheat | - |
| Phaseolus coccineus | - |
scarlet runner bean, L. | - |
| Phaseolus vulgaris | - |
wax bean, L. var.Bountiful | - |
| Vicia faba | - |
broad bean, L. var. Windsor | - |
| Vigna radiata | - |
mung bean, [L.] Wilczek, originally classified as Phaseolus aureus [L.] Roxb. | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Phaseolus vulgaris |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cotyledon | - |
Phaseolus vulgaris | - |
| cotyledon | - |
Vicia faba | - |
| cotyledon | - |
Vigna radiata | - |
| cotyledon | - |
Phaseolus coccineus | - |
| seedling | - |
Vigna radiata | - |
| shoot | - |
Vigna radiata | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| prephenate + NADP+ | - |
Phaseolus vulgaris | 4-hydroxyphenylpyruvate + CO2 + NADPH | - |
? | |
| prephenate + NADP+ | - |
Vicia faba | 4-hydroxyphenylpyruvate + CO2 + NADPH | - |
? | |
| prephenate + NADP+ | - |
Klebsiella aerogenes | 4-hydroxyphenylpyruvate + CO2 + NADPH | - |
? | |
| prephenate + NADP+ | - |
Vigna radiata | 4-hydroxyphenylpyruvate + CO2 + NADPH | - |
? | |
| prephenate + NADP+ | - |
Phaseolus coccineus | 4-hydroxyphenylpyruvate + CO2 + NADPH | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Phaseolus vulgaris |
| 7.5 | - |
- |
Vigna radiata |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 4 | 10.8 | - |
Phaseolus vulgaris |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 8 | maximum stability in this range at 22°C | Phaseolus vulgaris |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADP+ | NAD+ is ineffective in replacing NADP+ | Phaseolus vulgaris | |
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