Activating Compound | Comment | Organism | Structure |
---|---|---|---|
bovine serum albumin | - |
Klebsiella aerogenes |
General Stability | Organism |
---|---|
glycerol stabilizes | Klebsiella aerogenes |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-hydroxyphenylpyruvate | - |
Klebsiella aerogenes | |
AMP | - |
Klebsiella aerogenes | |
additional information | substrate analogues | Klebsiella aerogenes | |
NADH | - |
Klebsiella aerogenes |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
prephenate + NAD+ | Klebsiella aerogenes | biosynthesis of L-tyrosine | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Klebsiella aerogenes | - |
- |
- |
Purification (Comment) | Organism |
---|---|
chorismate mutase-prephenate dehydrogenase bifunctional enzyme | Klebsiella aerogenes |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
33 | - |
chorismate mutase-prephenate dehydrogenase bifunctional enzyme | Klebsiella aerogenes |
Storage Stability | Organism |
---|---|
-15°C, 0.02% sodium azide, N2-atmosphere, more than 0.1 mg/ml protein | Klebsiella aerogenes |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
prephenate + NAD+ | mechanism, kinetic studies | Klebsiella aerogenes | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
ir | |
prephenate + NAD+ | biosynthesis of L-tyrosine | Klebsiella aerogenes | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
ir |
Synonyms | Comment | Organism |
---|---|---|
chorismate mutase-prephenate dehydrogenase bifunctional enzyme | complex with EC 5.4.99.5 | Klebsiella aerogenes |