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Literature summary for 1.3.1.12 extracted from
- Terminal phenylalanine and tyrosine biosynthesis of Microtetraspora glauca (1989), Biol. Chem. Hoppe-Seyler, 370, 591-599.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4-hydroxymercuribenzoate | - |
Microtetraspora glauca |  |
| L-tyrosine | - |
Microtetraspora glauca | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 68000 | - |
gel filtration | Microtetraspora glauca |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| prephenate + NAD+ | Microtetraspora glauca | biosynthesis of L-tyrosine | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Microtetraspora glauca | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| together with arogenate dehydrogenase | Microtetraspora glauca |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| prephenate + NAD+ | - |
Microtetraspora glauca | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
| prephenate + NAD+ | biosynthesis of L-tyrosine | Microtetraspora glauca | 4-hydroxyphenylpyruvate + NADH + CO2 | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| additional information | NADP+ cannot substitute for NAD+ | Microtetraspora glauca | |
| NAD+ | - |
Microtetraspora glauca | |
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