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Literature summary for 1.3.1.101 extracted from
- Stereochemistry of reduction in digeranylgeranylglycerophospholipid reductase involved in the biosynthesis of archaeal membrane lipids from Thermoplasma acidophilum (2007), Bioorg. Chem., 35, 276-283.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli Rosetta (DE3) | Thermoplasma acidophilum |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 43000 | - |
x * 43000, SDS-PAGE | Thermoplasma acidophilum |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + 8 NAD(P)H + 8 H+ | Thermoplasma acidophilum | formation of 2,3-di-O-phytanylglyceryl phosphate, which is the basic core structure of archaeal membrane lipids | 2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + 8 NAD(P)+ | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Thermoplasma acidophilum | Q9HKS9 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Thermoplasma acidophilum |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + 8 NAD(P)H + 8 H+ | - |
Thermoplasma acidophilum | 2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + 8 NAD(P)+ | - |
? | |
| 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + 8 NAD(P)H + 8 H+ | formation of 2,3-di-O-phytanylglyceryl phosphate, which is the basic core structure of archaeal membrane lipids | Thermoplasma acidophilum | 2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + 8 NAD(P)+ | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 43000, SDS-PAGE | Thermoplasma acidophilum |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DGGGPL reductase | - |
Thermoplasma acidophilum |
| Ta0516m | - |
Thermoplasma acidophilum |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | the cofactor is bound to the enzyme in the ratio 1:1 | Thermoplasma acidophilum | |
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Release 2023.1 (January 2023)
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