Cloned (Comment) | Organism |
---|---|
fabK in expression plasmid | Streptococcus pneumoniae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | not inhibited by: triclosan | Streptococcus pneumoniae |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
34000 | - |
FabK, gene sequence | Streptococcus pneumoniae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Streptococcus pneumoniae | part of fatty acid synthesis reducing double bonds of a great varity of acyl thioesters | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus pneumoniae | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.066 | - |
- |
Streptococcus pneumoniae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
crotonyl-[acyl-carrier protein] + NADPH | substrate created by E. coli enzymes during assay | Streptococcus pneumoniae | butyryl-[acyl-carrier protein] + NADP+ | - |
? | |
additional information | part of fatty acid synthesis reducing double bonds of a great varity of acyl thioesters | Streptococcus pneumoniae | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | enzyme contains 0.8 mol FAD/enzyme, but functional role is not investigated | Streptococcus pneumoniae | |
NADH | also essential for activity, article leaves doubtful whether NADH or NADPH or both are cofactors | Streptococcus pneumoniae |