Cloned (Comment) | Organism |
---|---|
- |
Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
aurothioglucose | - |
Mus musculus | |
additional information | no inhibition by propylthiouracil | Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0000044 | - |
L-thyroxine | - |
Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-thyroxine + electron acceptor | Mus musculus | the enzyme is regulated at the pretranslational level | 3,3',5-triiodothyronine + iodide + reduced electron acceptor | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q9Z1Y9 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
colon | low level of activity | Mus musculus | - |
duodenum | low level of activity | Mus musculus | - |
heart | low level of activity | Mus musculus | - |
kidney | low level of activity | Mus musculus | - |
liver | low level of activity | Mus musculus | - |
lung | low level of activity | Mus musculus | - |
mammary gland | - |
Mus musculus | - |
prostate | low level of activity | Mus musculus | - |
testis | low level of activity | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-thyroxine + electron acceptor | - |
Mus musculus | 3,3',5-triiodothyronine + iodide + reduced electron acceptor | - |
? | |
L-thyroxine + electron acceptor | the enzyme is regulated at the pretranslational level | Mus musculus | 3,3',5-triiodothyronine + iodide + reduced electron acceptor | - |
? |
Synonyms | Comment | Organism |
---|---|---|
type II iodothyronine deiodinase | - |
Mus musculus |