KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0002 | 0.0006 | L-thyroxine | isoform III, 37°C, pH 6.0 | Rattus norvegicus | |
0.001 | - |
L-thyroxine | isoform II, 37°C, pH 6.0 | Rattus norvegicus | |
0.002 | 0.0035 | L-thyroxine | isoform I, 37°C, pH 6.8 | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | enzyme isoforms I, II | Rattus norvegicus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
enzyme isoforms I, II, and III | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Storage Stability | Organism |
---|---|
-20°C, presence of 3 mM dithiothreitol, stable for at least 6 weeks, after 3 months, loss of55% of activity | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-thyroxine + AH2 | - |
Rattus norvegicus | 3,5,3'-triiodo-L-thyronine + iodide + A + H+ | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5 | 6 | isoform III | Rattus norvegicus |
5.8 | 6.3 | isoform II | Rattus norvegicus |
6.8 | - |
isoform I | Rattus norvegicus |