Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | by activation of type 3 deiodinase during illness reduction of thyroid hormone levels | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
triiodothyronine | - |
Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
wild-type and type 3 deiodinase knockout mice, infected with Streptococcus pneumoniae | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3,3',5'-triido-L-thyronine + iodide + A + H+ | assay at pH 7.2 | Mus musculus | L-thyroxine + AH2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
type 3 deiodinase | - |
Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.2 | - |
assay at | Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | role in innate immune response, reduction of thyroid hormone levels during illness, protective role in defense against acute bacterial infection, probably by reinforcement of microbial killing capacity of neutrophils | Mus musculus |