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Literature summary for 1.21.99.3 extracted from

  • Olivares, E.L.; Marassi, M.P.; Fortunato, R.S.; da Silva, A.C.; Costa-e-Sousa, R.H.; Araujo, I.G.; Mattos, E.C.; Masuda, M.O.; Mulcahey, M.A.; Huang, S.A.; Bianco, A.C.; Carvalho, D.P.
    Thyroid function disturbance and type 3 iodothyronine deiodinase induction after myocardial infarction in rats a time course study (2007), Endocrinology, 148, 4786-4792.
    View publication on PubMed
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Application

Application Comment Organism
medicine type 3 deiodinase activity is robustly induced 1 week after myocardial infarction only in the infarcted myocardium and leads to an acute decrease in serum T4 and T3 after infarction Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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 male Wistar rats, healthy and subjected to myocardial infarction
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Source Tissue

Source Tissue Comment Organism Textmining
liver
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 Rattus norvegicus
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myocardium healthy and infarcted Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,5,3'-triiodothyronine + AH2 radioactive and unlabeled T3,in presence of 1 6-N-propylthiouracil, the products of deiodination are quantified by HPLC Rattus norvegicus 3,3'-diiodothyronine + iodide + A + H+
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 ?

Synonyms

Synonyms Comment Organism
type 3 deiodinase
-
 Rattus norvegicus
type 3 iodothyronine deiodinase
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 Rattus norvegicus