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Literature summary for 1.21.4.2 extracted from

  • Andreesen, J.R.
    Glycine reductase mechanism (2004), Curr. Opin. Chem. Biol., 8, 454-461.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40000
-
protein C, x * 40000 + x * 54000 Acetoanaerobium sticklandii
40000
-
protein C, x * 40000 + x * 54000 Treponema denticola
40000
-
protein C, x * 40000 + x * 54000 Tissierella creatinophila
54000
-
protein C, x * 40000 + x * 54000 Acetoanaerobium sticklandii
54000
-
protein C, x * 40000 + x * 54000 Treponema denticola
54000
-
protein C, x * 40000 + x * 54000 Tissierella creatinophila
200000 240000 protein C, gel filtration Acetoanaerobium sticklandii
200000 240000 protein C, gel filtration Treponema denticola
200000 240000 protein C, gel filtration Tissierella creatinophila

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glycine + phosphate + thioredoxin Acetoanaerobium sticklandii conservation of energy as acetyl phosphate acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
?
glycine + phosphate + thioredoxin Treponema denticola conservation of energy as acetyl phosphate acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
?
glycine + phosphate + thioredoxin Peptoclostridium acidaminophilum conservation of energy as acetyl phosphate acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
?
glycine + phosphate + thioredoxin Tissierella creatinophila conservation of energy as acetyl phosphate acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
?

Organism

Organism UniProt Comment Textmining
Acetoanaerobium sticklandii
-
three protein system consisting of proteins A,B, and C
-
Peptoclostridium acidaminophilum
-
three protein system consisting of proteins A,B, and C
-
Tissierella creatinophila
-
three protein system consisting of proteins A,B, and C
-
Treponema denticola
-
three protein system consisting of proteins A,B, and C
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glycine + phosphate + thioredoxin
-
Acetoanaerobium sticklandii acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
?
glycine + phosphate + thioredoxin
-
Treponema denticola acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
?
glycine + phosphate + thioredoxin
-
Peptoclostridium acidaminophilum acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
?
glycine + phosphate + thioredoxin
-
Tissierella creatinophila acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
?
glycine + phosphate + thioredoxin conservation of energy as acetyl phosphate Acetoanaerobium sticklandii acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
?
glycine + phosphate + thioredoxin conservation of energy as acetyl phosphate Treponema denticola acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
?
glycine + phosphate + thioredoxin conservation of energy as acetyl phosphate Peptoclostridium acidaminophilum acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
?
glycine + phosphate + thioredoxin conservation of energy as acetyl phosphate Tissierella creatinophila acetyl phosphate + NH3 + thioredoxin disulfide + H2O
-
?

Subunits

Subunits Comment Organism
More three protein system consisting of protein A (17000 Da), protein B (47000 Da or 48000 Da, later processed into two proteins of 22000 and 25000 Da), and protein C (40000 or 54000 Da) Acetoanaerobium sticklandii
More three protein system consisting of protein A (17000 Da), protein B (47000 Da or 48000 Da, later processed into two proteins of 22000 and 25000 Da), and protein C (40000 or 54000 Da) Treponema denticola
More three protein system consisting of protein A (17000 Da), protein B (47000 Da or 48000 Da, later processed into two proteins of 22000 and 25000 Da), and protein C (40000 or 54000 Da) Peptoclostridium acidaminophilum
More three protein system consisting of protein A (17000 Da), protein B (47000 Da or 48000 Da, later processed into two proteins of 22000 and 25000 Da), and protein C (40000 or 54000 Da) Tissierella creatinophila
multimer protein C, x * 40000 + x * 54000 Acetoanaerobium sticklandii
multimer protein C, x * 40000 + x * 54000 Treponema denticola
multimer protein C, x * 40000 + x * 54000 Tissierella creatinophila