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Literature summary for 1.21.3.2 extracted from

  • Rueffer, M.; Zenk, M.H.
    Berberine synthase, the methylenedioxy group forming enzyme in berberine synthesis (1985), Tetrahedron Lett., 26, 201-202.
No PubMed abstract available
Search for more literature for 1.21.3.2

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline
-
 Berberis stolonifera
cyanide
-
 Berberis stolonifera
p-phenanthroline
-
 Berberis stolonifera

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.002
-
 Columbamine
-
 Berberis stolonifera

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ an iron protein, oxidation of the O-methoxyphenol structure forms the methylenedioxy group of berberine, Fe2+ restores activity after dialysis against o-phenanthroline Berberis stolonifera

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
columbamine + O2 Berberis stolonifera berberine biosynthesis ?
-
 ir

Organism

Organism UniProt Comment Textmining
Berberis stolonifera
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Berberis stolonifera

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
columbamine + O2
-
 Berberis stolonifera berberine + H2O
-
 ir
columbamine + O2 berberine biosynthesis Berberis stolonifera ?
-
 ir
additional information
-
 Berberis stolonifera ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
70
-
-
 Berberis stolonifera

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.9
-
-
 Berberis stolonifera