Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.2.7.4 extracted from

  • Doukov, T.I.; Blasiak, L.C.; Seravalli, J.; Ragsdale, S.W.; Drennan, C.L.
    Xenon in and at the end of the tunnel of bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase (2008), Biochemistry, 47, 3474-3483.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.2.7.4

Crystallization (Commentary)

Crystallization (Comment) Organism
-
 Moorella thermoacetica

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Moorella thermoacetica 5739
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ni-Fe-S center
-
 Moorella thermoacetica

Organism

Organism UniProt Comment Textmining
Moorella thermoacetica
-
 formerly Clostridium thermoaceticum strain ATCC 39073
-

Purification (Commentary)

Purification (Comment) Organism
-
 Moorella thermoacetica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CO + H2O + acceptor
-
 Moorella thermoacetica CO2 + reduced acceptor
-
 ?
CO + H2O + acceptor
-
 Moorella thermoacetica CO2 + reduced acceptor
-
 r

Subunits

Subunits Comment Organism
heterotetramer x-ray crystallography Moorella thermoacetica

Synonyms

Synonyms Comment Organism
carbon monoxide dehydrogenase/acetyl-CoA synthase bifunctional enzyme Moorella thermoacetica
CODH/ACS
-
 Moorella thermoacetica
CODH/ACS bifunctional enzyme carbon monoxide dehydrogenase/acetyl-CoA synthase Moorella thermoacetica

Cofactor

Cofactor Comment Organism Structure
Ni-Fe-S center uses a Ni-Fe-S center called the C-cluster to reduce carbon dioxide to carbon monoxide and uses a second Ni-Fe-S center, called the A-cluster, to assemble acetyl-CoA from a methyl group, coenzyme A, and C-cluster-generated CO Moorella thermoacetica