Literature summary for 1.2.4.1 extracted from

Schreiner, M.E.; Fiur, D.; Holatko, J.; Patek, M.; Eikmanns, B.J.
E1 enzyme of the pyruvate dehydrogenase complex in Corynebacterium glutamicum: molecular analysis of the gene and phylogenetic aspects (2005), J. Bacteriol., 187, 6005-6018.

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Protein Variants

Protein Variants	Comment	Organism
additional information	enzyme-deficient mutant. Inactivation of enzyme gene leads to the inability to grow on glucose and the absence of enzymic and enzyme complex activities	Corynebacterium glutamicum

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.7	-	pyruvate	30°C, cell extract	Corynebacterium glutamicum

Organism

Organism	UniProt	Comment	Textmining
Corynebacterium glutamicum	Q8NNF6	analysis of enzyme phylogeny	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
pyruvate + CoA + NAD+	-	Corynebacterium glutamicum	acetyl-CoA + CO2 + NADH	-	?

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Release 2023.1 (January 2023)