Literature summary for 1.2.3.3 extracted from

Muller, Y.A.; Schumacher, G.; Rudolph, R.; Schulz, G.E.
The refined structures of a stabilized mutant and of wild-type pyruvate oxidase from Lactobacillus plantarum (1994), J. Mol. Biol., 237, 315-335.

Search for more literature for 1.2.3.3

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Lactiplantibacillus plantarum

Crystallization (Commentary)

Crystallization (Comment)	Organism
wild-type at 2.5 A resolution, triple mutant at 2.1 A resolution, hanging drop vapour diffusion technique	Lactiplantibacillus plantarum

Protein Variants

Protein Variants	Comment	Organism
P178S/S188N/A458V	stabilizes quaternary rather than tertiary structure	Lactiplantibacillus plantarum

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	-	Lactiplantibacillus plantarum

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
pyruvate + phosphate + O2 + H2O	Lactiplantibacillus plantarum	-	acetyl phosphate + CO2 + H2O2	-	?

Organism

Organism	UniProt	Comment	Textmining
Lactiplantibacillus plantarum	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
pyruvate + phosphate + O2 + H2O	-	Lactiplantibacillus plantarum	acetyl phosphate + CO2 + H2O2	-	?

Subunits

Subunits	Comment	Organism
tetramer	composed of four identical subunits, each subunit binds one FAD and one thiamine diphosphate-Mg2+, analysis from X-ray diffraction data	Lactiplantibacillus plantarum

Synonyms

Synonyms	Comment	Organism
POX	-	Lactiplantibacillus plantarum

Cofactor

Cofactor	Comment	Organism	Structure
FAD	-	Lactiplantibacillus plantarum
thiamine diphosphate	-	Lactiplantibacillus plantarum

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)