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Literature summary for 1.2.3.1 extracted from

  • Takei, M.; Kogure, S.; Yokoyama, C.; Kouzuma, Y.; Suzuki, Y.
    Identification of an aldehyde oxidase involved in indole-3-acetic acid synthesis in Bombyx mori silk gland (2019), Biosci. Biotechnol. Biochem., 83, 129-136 .
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.14
-
Indole-3-acetaldehyde pH 8, 25°C Bombyx mori

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
260000
-
PAGE Bombyx mori

Organism

Organism UniProt Comment Textmining
Bombyx mori Q17209 cf. EC 1.17.1.4
-

Source Tissue

Source Tissue Comment Organism Textmining
silk gland
-
Bombyx mori
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.697
-
substrate indole-3-acetalaldehyde, pH 8, 25°C Bombyx mori

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
indole-3-acetaldehyde + H2O + O2
-
Bombyx mori indole-3-acetic acid + H2O2
-
?

Subunits

Subunits Comment Organism
dimer 2 * 130000, SDS-PAGE Bombyx mori

Synonyms

Synonyms Comment Organism
IAO1
-
Bombyx mori

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
40
-
-
Bombyx mori

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
70
-
10 min, complete loss of activity Bombyx mori

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9
-
-
Bombyx mori

Cofactor

Cofactor Comment Organism Structure
FAD
-
Bombyx mori
molybdopterin protein contains a molybdopterin-binding domain Bombyx mori
[2Fe-2S]-center protein contains 2 2Fe-2S iron-sulfur-cluster-binding domains Bombyx mori

General Information

General Information Comment Organism
metabolism IAO1 causes the nonenzymatic conversion of tryptophan to indole-3-acetaldehyde and the enzymatic conversion of indole-3-acetalaldehyde to indole-3-acetic acid Bombyx mori