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Literature summary for 1.2.3.1 extracted from

  • Kundu, T.K.; Hille, R.; Velayutham, M.; Zweier, J.L.
    Characterization of superoxide production from aldehyde oxidase: an important source of oxidants in biological tissues (2007), Arch. Biochem. Biophys., 460, 113-121.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.2.3.1

Application

Application Comment Organism
medicine aldehyde oxidase can be an important basal source of superoxide that will be enhanced in disease settings where cellular aldehyde levels are increased Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
menadione
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
150000
-
 1 * 150000, SDS-PAGE Rattus norvegicus
290000
-
 gel filtration Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus Q9Z0U5
-
-

Purification (Commentary)

Purification (Comment) Organism
1667fold by gel filtration with a yield of 12%, to more than 98% purity Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.08
-
 liver homogenate Rattus norvegicus
1.8
-
 1667fold purified enzyme Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
p-dimethyl aminocinnamaldehyde + H2O + O2
-
 Rattus norvegicus ? + H2O2
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 150000, SDS-PAGE Rattus norvegicus